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polarized light microscope eclipse e600 pol  (Nikon)

 
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    Nikon polarized light microscope eclipse e600 pol
    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
    Polarized Light Microscope Eclipse E600 Pol, supplied by Nikon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polarized light microscope eclipse e600 pol/product/Nikon
    Average 90 stars, based on 1 article reviews
    polarized light microscope eclipse e600 pol - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis"

    Article Title: Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

    Journal: eLife

    doi: 10.7554/eLife.92275

    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light microscope at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
    Figure Legend Snippet: ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light microscope at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.

    Techniques Used: Injection, Concentration Assay, Staining, Light Microscopy, Standard Deviation, Saline, Comparison, TUNEL Assay



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    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
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    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
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    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
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    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
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    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light <t>microscope</t> at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.
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    Image Search Results


    ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light microscope at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.

    Journal: eLife

    Article Title: Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

    doi: 10.7554/eLife.92275

    Figure Lengend Snippet: ( A ) Time course of intra-articular α-mannosidase injection and unloading. Red arrows indicate the one-shot, intra-articular injection that was performed once a week. ( B ) Histological evaluation of knee articular cartilage 4 weeks after intermittent α-mannosidase infusion and 16 weeks after load removal. Scale bars, 50 μm. ( C ) Representative macroscopic assessment of the articular cartilage using mannosidase concentration. Scale bar, 1 cm. ( D ) Evaluation of the collagen orientation of reparative tissues at 4 weeks postoperatively. Sections stained with HE was viewed under a polarized light microscope at multiple angles (0°, 45°, and 90°). Scale bar, 200 μm. ( E ) OARSI scores at 4 weeks postoperatively on sections from the knee joint (n=6). ( F ) Tissue degeneration scores at each time point are based on mannosidase concentration. Data are shown as mean ± standard deviation. *p<0.05, **p<0.01 versus the saline group in ( E ), and versus 4 weeks in ( F ). In ( E ), the Welch t-test was used for statistical analysis. In ( F ), n=6 rabbits per group. One-way analysis of variance with Tukey’s multiple comparison test was used to perform statistical analysis. HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling.

    Article Snippet: To evaluate the collagen orientation of the repaired tissue at 16 weeks postoperatively, a supplemental evaluation using a polarized light microscope (PLM; ECLIPSE E600 POL; Nikon, Tokyo, Japan) was conducted ( ).

    Techniques: Injection, Concentration Assay, Staining, Light Microscopy, Standard Deviation, Saline, Comparison, TUNEL Assay